The Global Fund to Fight AIDS, Tuberculosis and Malaria

OVERVIEW: Established by the United Nations and endowed by the world’s wealthiest nations, the Global Fund to Fight AIDS, Tuberculosis and Malaria is a leading funder of global health initiatives. Focusing on AIDS/HIV, tuberculosis and malaria, the fund also partners with its grantees on research and evaluations of disease interventions. 

IP TAKE: The fund publishes extensive information about its work and results on its website and runs an open application process that begins with an eligibility assessment. This is an accessible funder that takes some risks in its grantmaking. To help your proposal stick out of a very competitive field, read more about the fund’s giving history and reach out to a program officer to learn more about how its giving is evolving.

PROFILE: The Global Fund to Fight AIDS, Tuberculosis, and Malaria was established in 2002 by the United Nations, then under the direction of Kofi Annan. It is funded by the world’s wealthiest nations and aims to halt the cycle of poverty and preventable disease that plagues the developing world. Grantmaking generally supports national centers for disease control, government ministries (including health ministries), multi-country initiatives and U.N. development programs, which often subcontract NGOs to oversee country-specific initiatives. The fund’s grantmaking focuses on three programmatic areas: HIV/AIDS, tuberculosis and malaria. Grants support initiatives for prevention, awareness and treatment of target diseases, as well as evaluations of the outcomes and efficaciousness of sponsored programs. Funding countries that are disproportionately affected by AIDS, tuberculosis and malaria.

Grants for Global Health

In its ongoing effort to treat and prevent tuberculosis, malaria and AID/HIV, the Global Fund gives to governments, health ministries and centers for disease control in Africa, Asia, Europe and Latin America, collaborating with 496 partners in 181 strategic locations. One Asian grantee partner is the Ministry of Public Health of the Islamic Republic of Afghanistan, which used funding to respond to strengthen its response to tuberculosis infection. In Colombia, the Empresa Nacional Promotora del Desarrollo Territorial used funding to enhance regional HIV programs, and in Sierra Leone, the Ministry of Health and Sanitation received a grant to expand malaria control interventions. In late 2023, the fund pledged $165 million over three years to Ukraine’s Ministry of Health to bolster its response to the tuberculosis and HIV/AIDS epidemics in the country that have been complicated because of the war. It also announced in early 2024, that it had committed $249 million in grants to help fight diseases in the Ivory Coast (Côte d’Ivoire); grantees include Save the Children, Alliance Côte d’Ivoire, and the Ministry of Health, Public Hygiene and Universal Health Coverage of Côte d’Ivoire.

Grants for Disease Research

In addition to funding prevention and treatment programs, the Global Fund partners with many of its grantees on program and intervention evaluations, sharing its data with the public via its online databases and publications. It is important to note that disease research funded by the Global Fund generally assesses the effectiveness and expedience of existing interventions as opposed to research on etiology, treatment, recovery or risk of target diseases. For examples of the Global Fund’s research, see its reports and data explorer pages. 

In 2020, the fund added $1 billion to its annual average of $4 billion in funding to combat the spread of the COVID-19 virus, and in 2023, it awarded $547 million in grants to groups in 40 countries through its COVID-19 Response Mechanism, which works “to mitigate the impact of the COVID-19 pandemic on programs to fight AIDS, tuberculosis (TB) and malaria.”

Important Grant Details:

The Global Foundation’s grantmaking generally tops $4 billion a year, with most grants ranging from $10 million to over $100 million. Grantmaking is limited to countries where HIV/AIDS, malaria and or tuberculosis infections are deemed problematic, and grants generally go to national governments, ministries of health and U.N. health programs. The fund maintains a results report and a data service on its website. 

Prospective grantees should consult the fund’s eligibility page before applying for funding. Funding guidelines and an applicant handbook are also available at the fund’s website. For general inquiries or application assistance, staff may be reached via email or online form

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